Erectile dysfunction (ED) is common with aging. Formerly ED treatment was offered mainly by urologists, but the approval and widespread use of phosphodiesterase inhibitors has enabled primary care clinicians to provide targeted ED treatment. Although large, multicenter clinical trials have shown efficacy and safety with these drugs, they are ineffective in 30–35% of men, may cause side-effects, and do not improve the underlying pathology. A thorough understanding of erectile physiology and causes of ED and a comprehensive treatment plan addressing all contributing factors may be more effective than pharmaceutical management and may improve aspects of psychological and physical health beyond erectile problems.
Effect of the Anti-Inflammatory Diet in People with Diabetes and Pre-Diabetes: A Randomized Controlled Feeding Study
Introduction: Inflammation underlies a variety of chronic medical conditions, including diabetes. The anti-inflammatory diet, one that excludes foods that may stimulate inflammation and includes foods that reduce inflammation, may improve inflammatory biomarkers in people with diabetes and pre-diabetes.
Study Design: Thirty participants with diabetes or pre-diabetes were randomized (2:1) in a controlled feeding study that compared the anti-inflammatory diet (n=20) to a control diet (n=10) based on the American Diabetes Association recommendations. Diets were matched for protein, carbohydrate, fat, and fiber content as closely as possible. Participants were fed an isocaloric diet for 2 weeks, followed by continued ad libitum feeding in their dietary group assignment for an additional 4 weeks. All meals were prepared by the study team.
Outcomes: Primary outcomes included inflammatory markers, including cytokines and hsCRP. Secondary outcomes included body weight and biomarkers for cardiovascular disease and diabetes.
Results: Both diets resulted in trends in reduced markers of inflammation, especially with weight loss. In addition, glucose, lipids, and triglycerides all trended downward, also non-significantly and equally in both groups.
Conclusion: Dietary change can improve inflammation as well as other cardiometabolic risk factors. In this study, the anti-inflammatory diet did not affect markers of inflammation more than the control diet.
There comes a point when you can safely taper down the intensity of the treatments, but you have to be at a level in which you feel comfortable, you have control over the disease. Of course, you do that within a framework where you have an integrated treatment plan and you’re treating everything you find that is related to the disease. Even though vitamin C is one of the most potent therapies, obviously that’s not the only therapy you use.
In a situation where a patient is doing watchful waiting, why not enhance their watchful period with optimizing their diet and nutrition, and potentially reducing their likelihood of having the cancer progress? In that situation the only side effects of proper dietary changes are good ones, such as reducing the likelihood of comorbidities like diabetes, obesity, or heart disease.
“It's a tremendous conference. When you deal with hormones, there's a lot of detail. I have been doing this now for nine years and I've learned a lot in this conference. There are so many people that bring different expertise and if you sit there and listen, you will find something new that you can apply in practice.”
“I highly recommend that doctors look into the conference for a number of reasons. First of all, the information is excellent and the practical techniques to help patients get better is there, but there is also the camaraderie. The people who come to these conferences are inspiring to me as a practitioner. That's worth just as much to me as the information.”