Restorative Medicine Digest

TUDCA and Neurodegeneration

TUDCA is safe and potentially effective in ALS, which is now the first neurodegenerative condition to be treated with hydrophilic bile acids. read more »

Fisetin and Lung Health

Fisetin has been shown to have a positive effect on the complex array of interconnected signaling mechanisms that play a key role in regulating aging and health. read more »

Senolytic Therapy and Cancer

Efforts to prevent senescence resulting from cancer treatment have led to the emerging field of senolytic drug development. The goal of potential senolytic drugs is to induce apoptosis in tumor cells or inhibit expression of the senescence-associated secretory phenotype (SASP). read more »

A Novel Role for Senolytic Therapies

The link between viral infections and cellular senescence has prompted researchers to investigate the efficacy of senolytic agents, which have been shown to induce apoptosis in senescent cells. read more »

Berberine in Cardiovascular and Metabolic Health

Both pre-clinical and clinical studies continue to shed light on berberine’s therapeutic potential, corroborating many of its traditional uses. read more »

Cardiovascular Health Update: Red Yeast Rice

Studies have shown that daily consumption of Red Yeast Rice lowers plasma levels of LDL cholesterol by 15-25% within six to eight weeks. read more »

LDL Oxidation: A Risk Factor for Atherosclerosis

Oxidation of low-density lipoprotein (LDL) particles plays a key role in the development and progression of atherosclerosis. read more »

Berberine and Neurological Health

Modern-day research continues to shed light on the multiple cellular targets that berberine modulates, with increasing attention being paid to the potential role this remarkable compound may have in neurological health. read more »

Updates in Neurology: Nicotinamide Riboside and Mitochondrial Support

Therapeutic approaches that help regulate mitochondrial biogenenesis and mitophagy (a specialized form of autophagy that removes impaired mitochondria) could potentially have positive effects on the early stages and severity of neurodegenerative conditions, as well as supporting healthy aging in general. read more »

Updates in Neurology: Photobiomodulation Therapy

Photobiomodulation therapy, using the low-dose application of red or near-infrared light, is a noninvasive, therapeutic approach with the potential to stimulate, enhance, and repair cell and tissue architecture and restore function. read more »