Volume 6 of this Journal is a strong statement of our on-going commitment to provide the highest quality information in the form of research, clinical findings, and insights about restorative medicine to those who practice it, and who seek to ground what they do in a solid evidence base. This issue includes original research and several clinically oriented review articles.
This review examines the current research on autophagy and new drug and/or natural product approaches to enhancing partial autophagy that can help prevent neuronal death and the progression of neurodegenerative disease. The critical factor in brain health may be the balance of autophagy and cell death in maintaining viable neurons.
Because of its anti-inflammatory properties and promotion of nerve growth factor gene expression and neurite (axon or dendrite) outgrowth, H. erinaceus mycelium shows great promise for the treatment of Alzheimer’s and Parkinson’s diseases.
The Holy Grail of Curcumin and its Efficacy in Various Diseases: Is Bioavailability Truly a Big Concern?
This article dissects various contributing factors of curcumin bioavailability to identify possible causes for the discrepancies associated with its bioactivity and discuss how these new curcumin formulations could further improve its clinical usefulness.
The objective of this review is to summarize the effects and possible mechanisms of action of berberine when applied to various aspects of the cardiovascular system.
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