Lichten, Paradigm Shift: The Realization of New Medical Alternatives to Surgery for Endometriosis Quiz Please sign up for the course before taking this quiz. SHBG (serum binding hormone globulin) is elevated with estrogen excess, and Nandrolone binds to SHBG to lower estrogen levels via negative feedback of FSH and LH.1 False True Preliminary research shows that EDCs (Endocrine disrupting chemicals) may:1 Contribute to endometriosis All are true Accumulate in fat tissue Promote inflammation FAI (Free androgen index) increases with higher levels of testosterone.1 False True The author lists 9 hypotheses to the origin of endometriosis, including:1 Genetic causes and progesterone resistance All are true Genetic cause Retrograde menstruation