Cardiovascular Effects of Berberine: A Review of the Literature Quiz

Cardiovascular Effects of Berberine: A Review of the Literature Quiz

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This medical journal activity, Journal of Restorative Medicine 2019, from 03/01/2019 — 02/28/2020, has been reviewed and is acceptable for credit by the American Academy of Family Physicians. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Berberine lowers serum lipids through the following mechanisms:1
- Upregulation of LDLR expression
- Increasing fatty acid oxidation
- Promoting cholesterol excretion from liver into bile
- All are true
Berberine promotes endothelial homeostasis via the following mechanisms:1
- Berberine has alpha-2 adrenoceptor antagonist activity
- Berberine causes vascular smooth muscle relaxation
- Berberine causes endothelium dependent relaxation
- All are true
Berberine activates AMPK (5′ adenosine monophosphate-activated protein kinase), to support the following biochemical functions except:1
- Improving insulin sensitivity
- Inducing glycolysis
- Inhibiting respiratory mitochondrial complex 1
- Decreasing transcription factors
Berberine is an isolated alkaloid found in which of the following plants?1
- Mahonia aquifolium
- All contain berberine
- Hydrastis canadensis
- Berberis vulgaris