Journal of Restorative Medicine

Intermittent fasting (IF) has been shown to confer several physiological benefits, such as improved glucose regulation, stress resilience, suppression of inflammation, and in relation to cancer, tumor growth inhibition. These benefits can be accomplished through several mechanisms, such as induction of autophagy, mitophagy, autophagic cell death, and changes in the cellular metabolic environment. The nutritional restriction is a promising protocol to modulate autophagy and enhance the efficacy of anticancer therapies while protecting normal cells. IF may offer cancer patients an effective and less toxic adjuvant treatment for cancer. In addition, IF has shown benefits when combined with the use of chemotherapeutic drugs resulting in a decrease in side effects and an increase in the effectiveness of the drugs. This article discusses the evidence in support of dietary restriction, specifically IF, as a tool that may provide physiological and epigenetic benefits in the management of cancer.

This case study demonstrates the ability of thyroid-hormone therapy to help resolve eating disorders by fundamentally addressing motility, hunger, eating patterns, and hormone-associated psychological disturbance.

This review will discuss the evidence regarding how various environmental risk factors, such as infections agents and physical trauma, can lead to neuropathological changes by disrupting autophagy in ALS and potential treatment options in the management of each environmental factor previously discussed.

Low-dose combinations of curcumin and EGCG have a beneficial effect on regulating important cancer targets in HepG2 and SW1417 cell lines. The data suggest a supportive role for phytochemicals as complementary treatments to chemotherapy.

Background: Mind–body practices have a variety of health implications, including inflammatory modulation, cognitive improvement, and impact on neurofunction. Some of these effects have been demonstrated through rapidly developing technology and their impact on circulating blood levels of hormones and other molecules. As neurotrophic factors like brain-derived neurotrophic factor (BDNF) and hormones such as cortisol have been shown to play a role in cognitive function, this pilot study assessed the influence of a mind–body intervention, Qigong, on circulating levels in participants.

Human enjoyment of natural environmental settings is common to all cultures. It is a complex, evolutionary, psychophysiological response with notable potential to positively impact both physical and mental health of individuals and populations. Four decades of research have produced a large body of empirical and experimental studies demonstrating the benefits of contact with Nature. A sufficient evidence base now allows for meaningful systematic reviews and meta-analyses to begin to guide health recommendations. This is the first of three articles to review the state of the science on the potential health benefits of contact with Nature, covering Visual Nature, Forest Therapy, Gardening, Residential Greenspace, and Blue Space.