Journal of Restorative Medicine

Expanding the Evidence Base of Natural Medicine
Restorative Medicine Digest

Recent Articles

Intermittent Fasting and Cancer

Intermittent fasting (IF) has been shown to confer several physiological benefits, such as improved glucose regulation, stress resilience, suppression of inflammation, and in relation to cancer, tumor growth inhibition. These benefits can be accomplished through several mechanisms, such as induction of autophagy, mitophagy, autophagic cell death, and changes in the cellular metabolic environment. The nutritional restriction is a promising protocol to modulate autophagy and enhance the efficacy of anticancer therapies while protecting normal cells. IF may offer cancer patients an effective and less toxic adjuvant treatment for cancer. In addition, IF has shown benefits when combined with the use of chemotherapeutic drugs resulting in a decrease in side effects and an increase in the effectiveness of the drugs. This article discusses the evidence in support of dietary restriction, specifically IF, as a tool that may provide physiological and epigenetic benefits in the management of cancer.

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Decoding Amyotrophic Lateral Sclerosis: A Systems Biology Approach

This review will discuss the evidence regarding how various environmental risk factors, such as infections agents and physical trauma, can lead to neuropathological changes by disrupting autophagy in ALS and potential treatment options in the management of each environmental factor previously discussed.

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The Effect of Qigong Meditation on Serum Cortisol, BDNF, and Cognitive Function: A Pilot Study

Background: Mind–body practices have a variety of health implications, including inflammatory modulation, cognitive improvement, and impact on neurofunction. Some of these effects have been demonstrated through rapidly developing technology and their impact on circulating blood levels of hormones and other molecules. As neurotrophic factors like brain-derived neurotrophic factor (BDNF) and hormones such as cortisol have been shown to play a role in cognitive function, this pilot study assessed the influence of a mind–body intervention, Qigong, on circulating levels in participants.

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