Lichten, Paradigm Shift: The Realization of New Medical Alternatives to Surgery for Endometriosis Quiz Please sign up for the course before taking this quiz. SHBG (serum binding hormone globulin) is elevated with estrogen excess, and Nandrolone binds to SHBG to lower estrogen levels via negative feedback of FSH and LH.1 True False FAI (Free androgen index) increases with higher levels of testosterone.1 True False The author lists 9 hypotheses to the origin of endometriosis, including:1 Genetic causes and progesterone resistance Genetic cause Retrograde menstruation All are true Preliminary research shows that EDCs (Endocrine disrupting chemicals) may:1 Accumulate in fat tissue All are true Promote inflammation Contribute to endometriosis