Ashwagandha (Withania somnifera)

Indications Adrenal fatigue, anxiety, and insomnia. Mechanism of Action The withanolides, a group of steroidal lactones, are credited with adrenal supportive effects.1 Steroidal compounds in plants are structurally similar to human steroids, and many are noted to have numerous physiological effects. Animal studies suggest that ashwagandha is a γ-aminobutyric acid…

Arctic Rose, Golden Root (Rhodiola rosea)

Related Species Rhodiola imbricate, Rhodiola sachalinensis. Indications An adaptogen used to help the body adapt to physical, mental, and environmental stresses; increase energy, stamina, strength, and mental capacity; improve athletic performance and sexual function; and balance mood for depressive and anxious states. Mechanism of Action Rhodiola root contains phenylpropanoids and…

Holy Basil, Tulsi (Ocimum sanctum)

Indications To improve general health and vitality as an adaptogen, adrenal fatigue, stress, anxiety, depression, diabetes, poor circulation, infections, colds, flu, and fever. Mechanism of Action The mechanisms of action of Ocimum sanctum have not yet been thoroughly investigated. Chemical constituent assays have identified the ocimumosides and cerebrosides active in…

Licorice (Glycyrrhiza glabra 1)

Indications Adrenal-related fatigue and hypotension. Mechanism of Action Glycyrrhiza contains steroidal saponins credited with many of the supportive effects on the adrenal glands and hypothalamic–pituitary–adrenal (HPA) axis. Many adaptogenic plants possess steroidal saponins shown to exert immunomodulating and anabolic activities.1 As a general group of plant steroid-like compounds, saponins have…

Siberian Ginseng, Eleuthero (Eleutherococcus senticosus/ Acanthopanax senticosus)

Indications Fatigue, poor stamina, and stress intolerance. Used for adrenal support, nervous and mood disorders such as depression, mental fatigue, and poor concentration and is a traditional remedy to improve immune function in both chronic and acute infections. Mechanism of Action Much of medicinal actions of Eleutherococcus are credited to…