Berberine

Indications Dysbiosis, diabetes, obesity, hypercholesterolemia, hyperlipidemia, and inflammatory bowel disease. Mechanism of Action Berberine is a compound found in the protoberberine group of isoquinoline alkaloids, and is considered the major active component present in several plant species.1 Besides antioxidant, antimicrobial, and anti-inflammatory effects,2 recent studies have shown that berberine and…

Triphala (Combination of Terminalia bellirica, Terminalia chebula, and Emblica officinalis)

Indications Hyperlipidemia, atherosclerosis, diabetes, obesity, digestive disorders, dyspepsia, diarrhea, dysentery, joint pain, and osteoarthritis. Also used as an anti-inflammatory and antimicrobial. Mechanism of Action Triphala inhibits lipid peroxide and promotes scavenging of hydroxyl and superoxide radicals in vitro.1 The precise mechanisms of its antiobesity effects have not yet been elucidated.…

Milk Thistle (Silybum marianum 1)

Indications Supporting liver function and metabolism of glucose in diabetes, metabolic syndrome, hyperglycemia, and insulin resistance. Mechanism of Action Nearly all of the research on Silybum has focused on the silymarin complex, a mixture of flavonolignans obtained from the seeds. Silymarin includes the individual flavonolignans silybin A and silybin B…

Prickly Pear Cactus Fruits (Opuntia ficus indica, vulgaris, dillenii)

Indications Diabetes, obesity, hyperlipidemia, atherosclerosis, diabetes-related heart disease, and metabolic syndrome. Mechanism of Action The bright magenta-to-orange colors of various species of Opuntia fruits is partly because of the presence of betalains,1 so named because they also occur in beets (Beta vulgaris). The betalains include betacyanins and betaxanthins, such as…

Holy Basil, Tulsi (Ocimum sanctum)

Indications To improve general health and vitality as an adaptogen, adrenal fatigue, stress, anxiety, depression, diabetes, poor circulation, infections, colds, flu, and fever. Mechanism of Action The mechanisms of action of Ocimum sanctum have not yet been thoroughly investigated. Chemical constituent assays have identified the ocimumosides and cerebrosides active in…