Milk Thistle (Silybum marianum 3)

Indications Hyperlipidemia supporting liver function and metabolism of glucose, lipids, and hormones. Liver disease including cirrhosis, cancer prevention, hepatitis, and viral-induced inflammation and protection from exogenous chemicals and toxins1 (parenteral preparations have become established as a viable treatment to save the liver after acute ingestion of hepatotoxins such as poison…

Milk Thistle (Silybum marianum 2)

Indications Liver disease including cirrhosis, cancer prevention, supporting liver function and metabolism of glucose (e.g., diabetes, metabolic syndrome, hyperglycemia, and insulin resistance), lipids (hyperlipidemia) and hormones, hepatitis and viral-induced inflammation, and protection from exogenous chemicals and toxins1 (parenteral preparations have become established as a viable treatment to save the liver…

Milk Thistle (Silybum marianum 1)

Indications Supporting liver function and metabolism of glucose in diabetes, metabolic syndrome, hyperglycemia, and insulin resistance. Mechanism of Action Nearly all of the research on Silybum has focused on the silymarin complex, a mixture of flavonolignans obtained from the seeds. Silymarin includes the individual flavonolignans silybin A and silybin B…

Saw Palmetto (Serenoa repens)

Indications Genitourinary health and symptoms of conditions including benign prostatic hyperplasia, chronic nonbacterial prostatitis, and chronic pelvic pain syndrome. Hormonal modulator of estrogen and testosterone, polycystic ovarian syndrome with hirsutism. Mechanism of Action Pharmacological effects of Saw Palmetto extract include a1 adrenoreceptor-inhibitory properties, anti-inflammatory properties, antiproliferative activity, inhibition of 5α-reductase,…

Skullcap (Scutellaria lateriflora)

Indications Insomnia, anxiety, and nervous tension. Mechanism of Action The above-ground parts, principally the leaves and flowers, are used medicinally. Two important flavonoids found in Scutellaria are baicalin and wogonin. They are thought to be GABAergic, binding to the benzodiazepine site of the γ-aminobutyric (GABA) receptor, and thereby have a…

Rosmarinic Acid

Derivation Rosmarinus officinalis, Perilla frutescens, Prunella vulgaris, Melissa officinalis, Salvia, Borago officinalis, Lithosperma, Lycopus virginicus, Thymus vulgaris, Mentha piperita. Indications Rosmarinic acid’s effects on T cells and the release of inflammatory cytokines are shown to benefit chronic inflammatory disease, acute and chronic allergic phenomena, and autoimmune diseases. Rosmarinic acid has…

Arctic Rose, Golden Root (Rhodiola rosea)

Related Species Rhodiola imbricate, Rhodiola sachalinensis. Indications An adaptogen used to help the body adapt to physical, mental, and environmental stresses; increase energy, stamina, strength, and mental capacity; improve athletic performance and sexual function; and balance mood for depressive and anxious states. Mechanism of Action Rhodiola root contains phenylpropanoids and…

Reishi Mushroom, Lingzhi (Ganoderma lucidum)

Indications Reishi Mushroom has been used for bronchitis, high blood pressure, chronic hepatitis, and nephritis. Its beneficial effects also include anti-atherosclerotic, hypolipidemic, anti-diabetic, anti-aging, anti-fungal, anti-viral (specifically herpes and HIV).1a It is indicated for prevention and treatment of cardiovascular disease. Mechanism of Action Reishi Mushroom has been used for bronchitis,…

Dì huáng (Rehmannia glutinosa Dì huáng)

Indications Allergic, inflammatory, and autoimmune conditions including asthma, urticaria, eczema, hayfever, rheumatoid arthritis, chronic renal disease, thyroid disease, and multiple sclerosis. Mechanism of Action Oligosaccharides: Rehmannia contains raffinose family oligosaccharides that are found in many plants and are credited with immune-stimulating properties.1 Raffinose oligosaccharides are difficult to digest and often…

Red Yeast Rice, Xuezhikang (Monascus purpureus)

Indications Hyperlipidemia and associated conditions such as renal damage, cardiovascular disease, and prevention of and recovery from myocardial infarction. Mechanism of Action Monascus purpureus acts act as a natural HMG-CoA reductase inhibitor.1,2,3 It regulates serum triglycerides, total cholesterol, and LDL-cholesterol (LDL-C) as well as the expression of inflammatory transcription factors.…

African Snake Root, Indian Snake Root (Rauwolfia vomitoria, R. serpentina)

Traditional Uses Hypertension and arrhythmia. Mechanism of Action Rauwolfia’s effects on the heart include decreasing myocardial excitability, inhibiting atrial-ventricular conduction, and extending the refractory period of the heart rhythm.1 Much of the medicinal effects of Rauwolfia serpentina and Rauwolfia vomitoria have been attributed to the hypotensive indole alkaloid reserpine.2 Additional alkaloids found in Rauwolfia roots include the…

Kudzu (Pueraria mirifica, Pueraria lobata)

Indications Menopausal symptoms; general female reproductive health; support of bone, hair, and fingernails; sexual longevity including vaginal lubrication; and enhanced breast size. Mechanism of Action Pueraria contains numerous isoflavones that are phytosterols, plant compounds with steroid-like effects. The phytosterols include β-sitosterol, coumestrol, genistein, daidzein, formononetin, puerarin, and miroesterol.1,2,3,4 Miroesterol is…