Indications Polycystic Ovarian Syndrome (PCOS)1,2,3 Mechanism of Action Vitex agnus castus fruits contain flavonoid glycosides such as casticin, vitexin, penduletin, orientin, and apigenin; the iridoid compounds aucubin,4 agnuside,5,6 agnucastosides A, B, and C, mussaenosidic acid, and hydroxybenzoylmussaenosidic acid7; and labdane diterpene alkaloids such as vitexlactams A, B, and C8 and…
Indications Menopause, menstrual, and fertility disorders in women. Premenstrual syndrome (PMS), mastalgia, gynecomastia in men, adolescent acne, amenorrhea, ovarian cysts, hot flashes, menstrual bleeding irregularities.1,2,3 Mechanism of Action Vitex agnus castus fruits contain flavonoid glycosides such as casticin, vitexin, penduletin, orientin, and apigenin; the iridoid compounds aucubin,4 agnuside,5,6 agnucastosides A,…
Indications Nutritive and fertility tonic, menopausal symptoms, premenstrual syndrome. Mechanism of Action Legume isoflavones are structurally similar to 17β-estradiol and are natural ligands of α and β estrogen nuclear receptors.1 Genistein, daidzein, and formononetin are three isoflavones that occur in Trifolium, and they are the most studied of all isoflavones.…
Indications Genitourinary health and symptoms of conditions including benign prostatic hyperplasia, chronic nonbacterial prostatitis, and chronic pelvic pain syndrome. Hormonal modulator of estrogen and testosterone, polycystic ovarian syndrome with hirsutism. Mechanism of Action Serenoa berries contain approximately 1.5% volatile oil of which 63% are free fatty acids and 38% are…
Indications Menopausal symptoms; general female reproductive health; support of bone, hair, and fingernails; sexual longevity including vaginal lubrication; and enhanced breast size. Mechanism of Action Pueraria contains numerous isoflavones that are phytosterols, plant compounds with steroid-like effects. The phytosterols include β-sitosterol, coumestrol, genistein, daidzein, formononetin, puerarin, and miroesterol.1,2,3,4 Miroesterol is…
