High Blood Pressure: A Major Risk Factor for Heart Failure
Over time, increased hemodynamic stress on the heart from high blood pressure leads to the compensatory development of left ventricular hypertrophy. read more »
Restorative Medicine Digest
Quarterly Newsletter
The Role of Viral Infection in Heart Failure
Mounting evidence suggests that some viruses can persist in heart tissue after an initial infection, and become reactivated under certain conditions, triggering a cell-mediated immune response that leads to myocarditis and, potentially, dilated cardiomyopathy. read more »
TUDCA and Neurodegeneration
TUDCA is safe and potentially effective in ALS, which is now the first neurodegenerative condition to be treated with hydrophilic bile acids. read more »
Fisetin and Lung Health
Fisetin has been shown to have a positive effect on the complex array of interconnected signaling mechanisms that play a key role in regulating aging and health. read more »
Senolytic Therapy and Cancer
Efforts to prevent senescence resulting from cancer treatment have led to the emerging field of senolytic drug development. The goal of potential senolytic drugs is to induce apoptosis in tumor cells or inhibit expression of the senescence-associated secretory phenotype (SASP). read more »
A Novel Role for Senolytic Therapies
The link between viral infections and cellular senescence has prompted researchers to investigate the efficacy of senolytic agents, which have been shown to induce apoptosis in senescent cells. read more »
Berberine in Cardiovascular and Metabolic Health
Both pre-clinical and clinical studies continue to shed light on berberine’s therapeutic potential, corroborating many of its traditional uses. read more »
Cardiovascular Health Update: Red Yeast Rice
Studies have shown that daily consumption of Red Yeast Rice lowers plasma levels of LDL cholesterol by 15-25% within six to eight weeks. read more »
LDL Oxidation: A Risk Factor for Atherosclerosis
Oxidation of low-density lipoprotein (LDL) particles plays a key role in the development and progression of atherosclerosis. read more »
Berberine and Neurological Health
Modern-day research continues to shed light on the multiple cellular targets that berberine modulates, with increasing attention being paid to the potential role this remarkable compound may have in neurological health. read more »