Mounting evidence suggests that some viruses can persist in heart tissue after an initial infection, and become reactivated under certain conditions, triggering a cell-mediated immune response that leads to myocarditis and, potentially, dilated cardiomyopathy. read more »
TUDCA is safe and potentially effective in ALS, which is now the first neurodegenerative condition to be treated with hydrophilic bile acids. read more »
Fisetin has been shown to have a positive effect on the complex array of interconnected signaling mechanisms that play a key role in regulating aging and health. read more »
Efforts to prevent senescence resulting from cancer treatment have led to the emerging field of senolytic drug development. The goal of potential senolytic drugs is to induce apoptosis in tumor cells or inhibit expression of the senescence-associated secretory phenotype (SASP). read more »
The link between viral infections and cellular senescence has prompted researchers to investigate the efficacy of senolytic agents, which have been shown to induce apoptosis in senescent cells. read more »
Both pre-clinical and clinical studies continue to shed light on berberine’s therapeutic potential, corroborating many of its traditional uses. read more »
Modern-day research continues to shed light on the multiple cellular targets that berberine modulates, with increasing attention being paid to the potential role this remarkable compound may have in neurological health. read more »
Therapeutic approaches that help regulate mitochondrial biogenenesis and mitophagy (a specialized form of autophagy that removes impaired mitochondria) could potentially have positive effects on the early stages and severity of neurodegenerative conditions, as well as supporting healthy aging in general. read more »