Gastroenterology

ABSTRACT The powdered rhizome of turmeric has been extensively used in India and other South Asian cuisines, and is an integral part of Ayurvedic medicine for a broad range of conditions. In particular, curcumin, a major active component of turmeric, is one of the most studied botanicals for its anti-inflammatory, anti-oxidant and anti-cancer properties. Despite its well-documented therapeutic efficacy, for years the limited systemic bioavailability of curcumin has hindered its development as a potential therapeutic agent. However, recent introduction of unique extraction processes and various delivery methods has resulted in the development of new curcumin formulations and significantly improved its ...
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ABSTRACT Even though plants containing the alkaloid berberine have been used in Ayurvedic and Chinese medicine for over 2500 years, berberine’s potential cardiovascular and metabolic effects have been studied only in the recent past. The objective of this review is to summarize the effects and possible mechanisms of action of berberine when applied to various aspects of the cardiovascular system. Evidence is presented from experimental studies, clinical trials, and meta-analyses accessed via PubMed. Further research is needed, particularly clinical trials, but a growing body of evidence suggests an important role for berberine in the treatment of dyslipidemia, type 2 diabetes, ...
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ABSTRACT Obesity has become a major health problem due to its increasing prevalence and its association with chronic disorders that include type 2 diabetes, atherosclerosis, cardiovascular disease, and cancer. Although obesity is a result of a long-term imbalance between dietary intake and energy expenditure, dietary-induced alterations in the gut microbiome play an important role in the onset and development of this condition. Human and animal intestines contain trillions of microbes, defined as the gut microbiome or microbiota. The microbiome is largely responsible for the health of the host and varies with diet, host genotype, sex, and age. The normal gut ...
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Traditional herbal medicine has gained increasing attention as alternative therapy for the treatment of liver disease, which has become a global health problem associated with the increased prevalence of harmful chemicals in the environment and the use of pharmaceuticals known to have detrimental effects on liver function as well as alcohol abuse. Herbal derived medicines such as Turmeric (Curcuma longa), Guduchi (Tinospora cordifolia), Amla (Emblica officinalis), Milk Thistle (Silybum marianum), Madder (Rubia tinctorum), Andrographis (Andrographis paniculata), Bupleurum and Azadirachta indica have shown hepatoprotective and regenerative effects mainly associated with their antioxidant and anti-inflammatory properties, and they have been used ...
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