An Integrative Approach to Hypertension: A Comprehensive Review of Antihypertensive Nutrients and Botanicals

We conducted a comprehensive review of the most current data available on the antihypertensive effects of 29 different nutraceuticals. All of the reviewed botanical and nutrient supplements, with the exception of French maritime pine bark extract and maitake (Grifola frondosa), have been demonstrated to effectively lower blood pressure in humans with good tolerability.

To Stent or Not To Stent: Focusing on the ISCHEMIA Trial to Redefine Treatment in Stable Ischemic Heart Disease

Ischemic heart disease is the number one cause of mortality in both genders. Despite substantial gains in reducing mortality from cardiovascular disease, its prevalence is on the rise. Although percutaneous coronary revascularization procedures revolutionized the approach to acute coronary artery disease (CAD), their role in stable, chronic disease is less defined. As many more patients live on with stable forms of CAD, it is imperative that practitioners understand current evidence for and against revascularization, and develop a holistic, integrative approach to CAD. We examine current knowledge guiding decision-making in chronic CAD, and expand upon potential use of integrative approaches to chronic CAD.

The Role of Vitamin K2 in Bone and Cardiovascular Health

Vitamin K is an essential nutrient present in plants, animals, and fermented products that plays an important role in a number of biological systems. Recent evidence suggests that vitamin K has potential health benefits far beyond its role in activating coagulation factors. It appears that vitamin K2 (menaquinones) play an important role in optimal bone and cardiovascular health.

Chelation Therapy for Cardiovascular Disease: Bringing it Back to the Future

Chelation therapy, a treatment long undervalued by conventional medicine, has been used by alternative medicine practitioners to alleviate various metabolic toxicities. In particular, there has been significant controversy around its use in patients with coronary artery disease. We performed a focused review of the recent National Institute of Health (NIH)…

Progesterone Within Ovulatory Menstrual Cycles Needed for Cardiovascular Protection: An Evidence-Based Hypothesis

Abstract Women experience acute myocardial infarctions (AMI) 10 years later than men – evidence that estrogen is protective is not consistent. Ovulatory disturbances (low progesterone but normal estradiol levels) silently occur in >33% of all cycles. Progesterone-based (cycle-timed serum or saliva) levels or urinary metabolite excretions are necessary to diagnose…

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