This review will discuss the evidence regarding how various environmental risk factors, such as infections agents and physical trauma, can lead to neuropathological changes by disrupting autophagy in ALS and potential treatment options in the management of each environmental factor previously discussed.
Low-dose combinations of curcumin and EGCG have a beneficial effect on regulating important cancer targets in HepG2 and SW1417 cell lines. The data suggest a supportive role for phytochemicals as complementary treatments to chemotherapy.
Mind–body practices have a variety of health implications, including inflammatory modulation, cognitive improvement, and impact on neurofunction. Some of these effects have been demonstrated through rapidly developing technology and their impact on circulating blood levels of hormones and other molecules. As neurotrophic factors like brain-derived neurotrophic factor (BDNF) and hormones such as cortisol have been shown to play a role in cognitive function, this pilot study assessed the influence of a mind–body intervention, Qigong, on circulating levels in participants.
Human enjoyment of natural environmental settings is common to all cultures. It is a complex, evolutionary, psychophysiological response with notable potential to positively impact both physical and mental health of individuals and populations. Four decades of research have produced a large body of empirical and experimental studies demonstrating the benefits of contact with Nature. A sufficient evidence base now allows for meaningful systematic reviews and meta-analyses to begin to guide health recommendations. This is the first of three articles to review the state of the science on the potential health benefits of contact with Nature, covering Visual Nature, Forest Therapy, Gardening, Residential Greenspace, and Blue Space.
Parkinson’s disease (PD) is among the most common chronic neurodegenerative conditions, affecting 1% of those over 60 years of age, and involves motor and non-motor impairments. The purpose of this review is to highlight various nutrition and supplement interventions that may positively affect disease onset and progression, and that warrant further research.