Peripheral Thyroid Hormone Conversion and Its Impact on TSH and Metabolic Activity

Abstract There have been recent advances in understanding of the local control of thyroid activity and metabolism, including deiodinase activity and thyroid hormone membrane transport. The goal of this review is to increase the understanding of the clinical relevance of cellular deiodinase activity. The physiologic significance of types 1, 2…

Osteoporosis: The Need for Prevention and Treatment

Abstract Osteoporosis is a preventable, potentially crippling disease characterized by low bone density and increased bone fragility that affects millions of people. The seeds of this pernicious disease are sown during adolescence, when the skeleton is most active in absorbing dietary calcium and building up nearly all the bone mass…

The Calming Actions of Anemone Pulsatilla, Nepeta, and Rauvolfia

Abstract Pulsatilla, Nepeta, and Rauvolfia are important therapeutic agents with nerve-calming effects. Although not as strong as anxiolytic drugs, these herbal remedies are gentle and safe treatments for anxiety and insomnia. They can improve sleep, reduce mood swings and irritability, and moderate the stress-induced ‘fight-or-flight’ state. Theoretical concerns regarding adverse…

The Safety of Phytoestrogens in Menopause, Prostate and Breast Cancer

Abstract Plant based natural products have been proposed as alternatives to the use of hormones for the treatment of menopausal symptoms, which has been associated with an increased risk of breast cancer and coronary artery disease. Specific herbal compounds such as Thai Kudzu root (Pueraria mirifica) have shown beneficial effects…

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