Iodine is an essential trace mineral that is necessary for thyroid hormone production. With the prevalence of iodine deficiency worldwide, universal salt iodization programs were successfully implemented to reduce the incidence of iodine deficiency disorders; however, unexpected increases in the prevalence of thyroid autoimmunity occurred, and iodine excess was implicated as the causative factor. Despite these observations, epidemiological studies are inconsistent, and the etiology of autoimmune thyroid disease remains undefined. A review of observational and in vitro studies revealed that iodine alone is not responsible for thyroid autoimmunity.
Ischemic heart disease is the number one cause of mortality in both genders. Despite substantial gains in reducing mortality from cardiovascular disease, its prevalence is on the rise. Although percutaneous coronary revascularization procedures revolutionized the approach to acute coronary artery disease (CAD), their role in stable, chronic disease is less defined. As many more patients live on with stable forms of CAD, it is imperative that practitioners understand current evidence for and against revascularization, and develop a holistic, integrative approach to CAD. We examine current knowledge guiding decision-making in chronic CAD, and expand upon potential use of integrative approaches to chronic CAD.
Vitamin K is an essential nutrient present in plants, animals, and fermented products that plays an important role in a number of biological systems. Recent evidence suggests that vitamin K has potential health benefits far beyond its role in activating coagulation factors. It appears that vitamin K2 (menaquinones) play an important role in optimal bone and cardiovascular health.
Yoga is a holistic mind‐body practice used for physical and mental health, which is most commonly looked upon by educators as a wellness program for students. This study aims to analyze whether pre-adolescent school students who practiced yoga performed better in attention and memory tasks in comparison with controls that did not practice yoga.
We conducted a comprehensive review of the most current data available on the antihypertensive effects of 29 different nutraceuticals.
Background: Vitamin D is important for musculoskeletal health and may have significant implications for maintaining physical activity in elderly patients. Our goal was to investigate whether serum 25-hydroxyvitamin D (25OHD) levels are associated with pre-operative physical activity in patients who are offered elective knee or hip joint replacement surgery. Methods:…
This is our most exciting issue to date. We continue our mission to bring you the most relevant clinical information and concepts regarding restorative medicine. We begin this issue with several original research articles in the areas of bone health, inflammation, and prostate cancer. Sadeq Quraishi, MD, MHA, MMSc, Elizabeth…
Obesity is a major issue in developed countries. Regulating thyroid hormones is a growingly popular adjunct in a comprehensive approach towards weight loss. Despite growing popularity, there is a lack of knowledge about underlying pathways. This review investigates the thermogenic properties of thyroid hormone on brown adipose tissue (BAT), white…
Abstract Autoimmune thyroid diseases, including Graves’ disease and Hashimoto’s thyroiditis, are the most common autoimmune conditions in humans. There is significant morbidity associated with thyroid autoimmunity, and typically ongoing management is required to control disease presentation and reduce sequelae. Thyroid tissues contain the highest concentration of selenium in the body,…
Abstract Nutrigenomics is the study of the effects of food and food constituents on gene expression. The study of nutrigenomics may have a major impact in the development of tailor-made food, supplements and beverage products in the near future. The “genetic nutritioneering” concept summarizes the information on how diet, supplements,…
Abstract In the following paper, we will review the available literature on synergy and additive effects involving medicinal herbs and herbal extracts. Several types of synergistic interactions are discussed, including apparently inactive constituents enhancing the effects of apparently active constituents within and between herbal medicines, various herbal compounds altering the…
Abstract Rosmarinic acid (RosA) is an ester of caffeic acid and 3,4-dihydroxyphenylactic acid. RosA has a number of beneficial biological activities, including antiviral, antibacterial, anti-inflammatory, and antioxidant properties. Oxidative stress is recognized as a common factor in many neurodegenerative diseases and is a proposed mechanism for age-related degenerative processes as…
